Lysine acetylation is a post-translational modification that involves the addition of an acetyl group to lysine residues in proteins. This modification plays a crucial role in regulating various cellular processes, including gene expression, chromatin remodeling, and protein stability. Lysine acetylation is mediated by enzymes known as lysine acetyltransferases (KATs) and removed by lysine deacetylases (KDACs). Dysregulation of lysine acetylation has been implicated in the development of various diseases, including cancer and neurodegenerative disorders. Study of lysine acetylation is an important area of research in the field of epigenetics and post-translational modifications.